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GENE - TERM ANNOTATION REPORT

RGD ID: 3281
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pde4d
Name: phosphodiesterase 4D
Acc ID: GO:0097110
Term: scaffold protein binding
Definition: Binding to a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
Definition Source(s): GOC:BHF, GOC:sjp, PMID:10433269, Wikipedia:Scaffold_protein
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde4denablesISOPDE4D (Homo sapiens)1624291RGDUniProtKB:P63244 UniProtKB:Q9WVC7 PMID:15182229 PMID:20819076

PMID:15182229 PMID:20819076
Pde4denablesIEAUniProtKB:Q08499 or ensembl:ENSP000003455021600115EnsemblGO_REF:0000107

GO_REF:0000107
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