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GENE - TERM ANNOTATION REPORT

RGD ID: 32716488
Species: Homo sapiens
RGD Object: Gene
Symbol: SPG7
Name: SPG7 matrix AAA peptidase subunit, paraplegin
Acc ID: DOID:2476
Term: hereditary spastic paraplegia
Definition: A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Familial_spastic_paraplegia "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:21623769 PMID:22964162 PMID:24727571 PMID:25741868 PMID:26467025 PMID:26756429 PMID:27217339 PMID:28362824 PMID:28492532 PMID:28812649 PMID:29057857 PMID:30533525 PMID:31345272
SPG7 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:25741868 PMID:26467025 PMID:28492532
SPG7 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:25741868 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Spastic Paraplegia, RecessivePMID:28492532
SPG7 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:16534102 PMID:25741868 PMID:26467025 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:16534102 PMID:25741868 PMID:26467025 PMID:28492532 PMID:32483926 PMID:33841295
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:23812641 PMID:25741868 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:21623769 PMID:22964162 PMID:25741868 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:18799786 PMID:22964162 PMID:24727571 PMID:25681447 PMID:25741868 PMID:27123479 PMID:28492532 PMID:29482223 PMID:30098094 PMID:32816195
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:18799786 PMID:21623769 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29970176
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:16534102 PMID:25741868 PMID:28492532 PMID:28832565
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:25741868 PMID:26626314 PMID:28492532 PMID:29915382 PMID:30747022
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:14985266 PMID:22571692 PMID:23065789 PMID:25497598 PMID:25681447 PMID:25741868 PMID:26467025 PMID:26626314 PMID:28492532 PMID:29246610 PMID:30533525 PMID:33624863
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:25741868 PMID:26626314
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:23065789 PMID:25741868 PMID:26626314 PMID:28444220 PMID:30533525
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:18200586 PMID:21623769 PMID:22964162 PMID:25741868 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:14722615 PMID:16357941 PMID:25741868 PMID:28492532 PMID:30098094
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Spastic Paraplegia, Recessive 
SPG7 IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:25741868
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:21623769 PMID:22964162 PMID:28492532 PMID:28832565 PMID:33841295
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:11222789 PMID:18799786 PMID:21623769 PMID:22554690 PMID:22571692 PMID:22964162 PMID:23065789 PMID:23269439 PMID:23812641 PMID:24033266 PMID:24466038 PMID:24727571 PMID:24731568 PMID:25741868 PMID:26094131 PMID:26260707 PMID:26374131 PMID:26467025 PMID:26626314 PMID:26671083 PMID:26756429 PMID:27084228 PMID:27165006 PMID:27217339 PMID:27260292 PMID:28492532 PMID:28608987 PMID:28832565 PMID:29026558 PMID:29915382 PMID:30533525 PMID:31068484 PMID:31345272 PMID:31433872 PMID:31692161 PMID:32161564
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:18563470 PMID:21623769 PMID:22964162 PMID:23065789 PMID:23733235 PMID:24033266 PMID:24727571 PMID:25681447 PMID:25741868 PMID:26467025 PMID:26756429 PMID:27957547 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:28492532 PMID:28832565
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:17576681 PMID:22571692 PMID:26467025 PMID:28492532 PMID:28832565 PMID:9536098
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:25741868 PMID:27217339 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:14985266 PMID:21623769 PMID:25741868 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:21623769 PMID:22964162 PMID:25741868 PMID:28492532 PMID:30747022
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:20108356 PMID:25741868 PMID:28492532 PMID:31407473
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:18200586 PMID:21623769 PMID:22571692 PMID:22964162 PMID:23065789 PMID:24727571 PMID:25681447 PMID:25741868 PMID:25976027 PMID:26467025 PMID:26626314 PMID:27084228 PMID:28362824 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:11478530 PMID:15507752 PMID:17384005 PMID:18414213 PMID:18799786 PMID:19841671 PMID:20186691 PMID:21623769 PMID:22964162 PMID:23065789 PMID:23269439 PMID:23733235 PMID:23812641 PMID:23953397 PMID:24401005 PMID:25034272 PMID:25133958 PMID:25277871 PMID:25741868 PMID:25850353 PMID:26244503 PMID:26365338 PMID:26467025 PMID:26626314 PMID:27016405 PMID:2779008 PMID:27790088 PMID:28492532 PMID:29431110 PMID:30533525 PMID:30747022 PMID:31980526 PMID:32153640 PMID:32270516 PMID:32447552
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Spastic Paraplegia, RecessivePMID:11222789 PMID:14985266 PMID:16534102 PMID:17661097 PMID:18200586 PMID:18799786 PMID:20186691 PMID:21623769 PMID:22571692 PMID:22964162 PMID:23065789 PMID:23269439 PMID:23733235 PMID:24033266 PMID:24727571 PMID:25497598 PMID:25681447 PMID:25741868 PMID:26467025 PMID:26506339 PMID:26626314 PMID:27084228 PMID:27165006 PMID:27957547 PMID:28362824 PMID:28444220 PMID:28492532 PMID:28832565 PMID:29026558 PMID:29057857 PMID:29246844 PMID:29915382 PMID:30098094 PMID:30537300 PMID:32581362 PMID:32973427
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:24033266 PMID:25741868 PMID:26467025 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:17646629 PMID:18200586 PMID:25741868 PMID:26467025 PMID:28492532
SPG7 IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Hereditary spastic paraplegiaPMID:11222789 PMID:16534102 PMID:23065789 PMID:24727571 PMID:25741868 PMID:26467025 PMID:28492532 PMID:32397312 PMID:32447552
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