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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3269
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pcna
Name: proliferating cell nuclear antigen
Acc ID: CHEBI:143205
Term: 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid
Definition: A perfluorinated compound that is 2-propoxypentanoic acid in which all 11 of the hydrogens attached to carbon atoms have been replaced by fluorine atoms. Used as an alternative to perfluorooctanoic acid in the fluoropolymer industry for years, its widespread environmental distribution, high bioaccumulation capability, and human exposure have caused great concern, particularly as its potential toxicity and health risk is still largely unknown.
Chemical ID: MESH:C000608800
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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