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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3243
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2rx6
Name: purinergic receptor P2X 6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2rx6decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of P2RX6 mRNAPMID:25181051 PMID:29097150 PMID:30816183 PMID:32528016
P2rx6increases expressionEXP 6480464CTDbisphenol A results in increased expression of P2RX6 mRNAPMID:27178563
P2rx6multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of P2RX6 mRNAPMID:26496021
P2rx6increases expressionISOP2rx6 (Mus musculus)6480464CTDbisphenol A results in increased expression of P2RX6 mRNAPMID:35598803
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