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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3197
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Npy
Name: neuropeptide Y
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Npyaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of NPY mRNAPMID:15977195 PMID:22298810
Npyincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of NPY mRNAPMID:15093705 PMID:23871856
Npymultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with LEP protein] affects the expression of NPY mRNA; AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NPY mRNA]PMID:15977195 PMID:23871856
Npyaffects expressionISONpy (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of NPY mRNAPMID:24680724
Npydecreases expressionISONpy (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of NPY mRNAPMID:19465110
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