GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Npy | affects expression | EXP | | 6480464 | CTD | Amphetamine affects the expression of NPY protein | PMID:16896163 | Npy | affects response to substance | EXP | | 6480464 | CTD | NPY protein affects the susceptibility to Amphetamine | PMID:16101753 | Npy | decreases expression | EXP | | 6480464 | CTD | Amphetamine results in decreased expression of NPY mRNA; Amphetamine results in decreased expression of NPY protein | PMID:12005258 PMID:15680483 PMID:15985714 PMID:16084549 PMID:16101753 PMID:16896163 PMID:25825358 | Npy | increases expression | EXP | | 6480464 | CTD | Amphetamine results in increased expression of NPY mRNA | PMID:15183010 | Npy | increases response to substance | EXP | | 6480464 | CTD | NPY protein results in increased susceptibility to Amphetamine | PMID:12005258 | Npy | multiple interactions | EXP | | 6480464 | CTD | FOS protein promotes the reaction [Amphetamine results in decreased expression of NPY mRNA]; Haloperidol promotes the reaction [Amphetamine results in decreased expression of NPY protein]; JUN protein promotes the reaction [Amphetamine results in decreased expression of NPY mRNA]; NPY mutant form promotes the reaction [Amphetamine results in increased expression of CARTPT mRNA]; PRKCA protein promotes the reaction [Amphetamine results in decreased expression of NPY mRNA]; S-ethyl glutathione inhibits the reaction [Amphetamine results in decreased expression of NPY mRNA]; S-ethyl glutathione inhibits the reaction [Amphetamine results in decreased expression of NPY protein] | PMID:15985714 PMID:16084549 PMID:16101753 PMID:25825358 | Npy | decreases response to substance | ISO | Npy (Mus musculus) | 6480464 | CTD | NPY protein results in decreased susceptibility to Amphetamine | PMID:12183048 | |
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