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GENE - TERM ANNOTATION REPORT

RGD ID: 3188
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Notch2
Name: notch receptor 2
Acc ID: GO:0001947
Term: heart looping
Definition: The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
Definition Source(s): GOC:dph, PMID:12094232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Notch2involved_inISONotch2 (Mus musculus)1624291RGDUniProtKB:Q01705 MGI:2661305 PMID:12730124

MGI:2661305 PMID:12730124
Notch2involved_inIEAUniProtKB:O35516 or ensembl:ENSMUSP000000787411600115EnsemblGO_REF:0000107

GO_REF:0000107
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