GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Notch2 | decreases acetylation | EXP | | 6480464 | CTD | alpha-naphthoflavone results in decreased acetylation of NOTCH2 promoter | PMID:29094188 | Notch2 | increases methylation | EXP | | 6480464 | CTD | alpha-naphthoflavone results in increased methylation of NOTCH2 promoter | PMID:29094188 | Notch2 | multiple interactions | EXP | | 6480464 | CTD | alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter] | PMID:29094188 | |
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