GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos2 | increases cleavage | EXP | | 6480464 | CTD | Gentamicins results in increased cleavage of NOS2 protein | PMID:22526374 | Nos2 | increases expression | EXP | | 6480464 | CTD | Gentamicins results in increased expression of NOS2 protein | PMID:15936777 PMID:16925772 PMID:17312373 PMID:18441258 PMID:19535489 PMID:30458643 | Nos2 | multiple interactions | EXP | | 6480464 | CTD | [Gentamicins results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide; Cholecalciferol inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; Melatonin inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Gentamicins results in increased expression of NOS2 protein] | PMID:16925772 PMID:17312373 PMID:22526374 PMID:30458643 | Nos2 | increases expression | ISO | Nos2 (Mus musculus) | 6480464 | CTD | Gentamicins results in increased expression of NOS2 mRNA; Gentamicins results in increased expression of NOS2 protein | PMID:29751043 | Nos2 | multiple interactions | ISO | Nos2 (Mus musculus) | 6480464 | CTD | Gentamicins promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of NOS2 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of NOS2 protein] | PMID:17442725 PMID:29751043 | |
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