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GENE - TERM ANNOTATION REPORT

RGD ID: 3168
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nf1
Name: neurofibromin 1
Acc ID: GO:0033024
Term: mast cell apoptotic process
Definition: Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
Definition Source(s): CL:0000097, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:12360215, PMID:16605130
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nf1acts_upstream_ofISONf1 (Mus musculus)1624291RGDMGI:96974 MGI:97583 MGI:99255 PMID:15039234

PMID:15039234
Nf1involved_inIEAUniProtKB:Q04690 or ensembl:ENSMUSP000000712891600115EnsemblGO_REF:0000107

GO_REF:0000107
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