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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myc
Name: MYC proto-oncogene, bHLH transcription factor
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mycdecreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of MYC mRNAPMID:20732408
Mycincreases expressionEXP 6480464CTDAcetaminophen results in increased expression of MYC mRNAPMID:12883083 PMID:17202758 PMID:17202762 PMID:17522070 PMID:22112502 PMID:32479839 PMID:33387578
Mycaffects expressionISOMyc (Mus musculus)6480464CTDAcetaminophen affects the expression of MYC mRNAPMID:15606129 PMID:17562736
Mycdecreases expressionISOMyc (Mus musculus)6480464CTDAcetaminophen results in decreased expression of MYC mRNAPMID:17585979
Mycdecreases expressionISOMYC (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of MYC mRNAPMID:20732408 PMID:9444671
Mycincreases expressionISOMyc (Mus musculus)6480464CTDAcetaminophen results in increased expression of MYC mRNAPMID:11264010 PMID:11752693 PMID:12540782 PMID:12958197 PMID:17562736 PMID:18544908 PMID:29174983
Mycincreases expressionISOMYC (Homo sapiens)6480464CTDAcetaminophen results in increased expression of MYC mRNAPMID:11896290 PMID:29067470
Mycmultiple interactionsISOMyc (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of MYC mRNA; O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of MYC mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MYC mRNA]PMID:12540782 PMID:17585979
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