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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3127
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mx1
Name: MX dynamin like GTPase 1
Acc ID: CHEBI:84491
Term: poly(I:C)
Definition: A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid.
Chemical ID: MESH:D011070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mx1increases expressionISOMX1 (Homo sapiens)6480464CTDPoly I-C results in increased expression of MX1 mRNAPMID:17669408 PMID:22558189 PMID:34051100
Mx1multiple interactionsISOMX1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]]; Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]PMID:34051100
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