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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:47807
Term: sulforaphane
Definition: An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Chemical ID: MESH:C016766
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1increases expressionISOAbcc1 (Mus musculus)6480464CTDsulforaphane results in increased expression of ABCC1 mRNAPMID:26454883
Abcc1multiple interactionsISOAbcc1 (Mus musculus)6480464CTDNFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of ABCC1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of ABCC1 protein]; sulforaphane results in increased expression of and results in increased activity of ABCC1 proteinPMID:26454883
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