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GENE - TERM ANNOTATION REPORT

RGD ID: 3098
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mme
Name: membrane metallo-endopeptidase
Acc ID: GO:0004222
Term: metalloendopeptidase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Definition Source(s): GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MmeenablesISOMME (Homo sapiens)1624291RGD PMID:15283675 PMID:2521388 PMID:27588448 PMID:6208535 PMID:6349683

PMID:15283675 PMID:2521388 PMID:27588448 PMID:6208535 PMID:6349683
MmeenablesIBAFB:FBgn0027570 or MGI:1343461 or PANTHER:PTN000199753 or Mmel1 (Rattus norvegicus) or UniProtKB:P08473 or UniProtKB:P0DPD6 or UniProtKB:P0DPE2 or UniProtKB:P23276 or UniProtKB:P428911600115GO_CentralGO_REF:0000033

GO_REF:0000033
MmeenablesIEAEC:3.4.24.111600115UniProtGO_REF:0000003

GO_REF:0000003
MmeenablesISSUniProtKB:P084731600115UniProtGO_REF:0000024

GO_REF:0000024
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