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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3084
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mgat3
Name: beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Acc ID: CHEBI:71045
Term: bisdemethoxycurcumin
Definition: A β-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups.
Chemical ID: MESH:C034786
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mgat3increases expressionISOMGAT3 (Homo sapiens)6480464CTDbisdemethoxycurcumin results in increased expression of MGAT3 mRNAPMID:19090986
Mgat3multiple interactionsISOMGAT3 (Homo sapiens)6480464CTD[bisdemethoxycurcumin analog co-treated with APP protein] results in increased expression of MGAT3 mRNA; [bisdemethoxycurcumin co-treated with APP protein] results in increased expression of MGAT3 mRNAPMID:22029407
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