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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3073
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc3a2
Name: solute carrier family 3 member 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7357166480464CTDBenzo(a)pyrene metabolite results in decreased expression of SLC3A2 mRNA

PMID:24356939
increases expressionISORGD:7357166480464CTDBenzo(a)pyrene results in increased expression of SLC3A2 mRNA

PMID:20106945, PMID:21632981, PMID:22316170, PMID:26238291, PMID:26621329
increases expressionISORGD:7357176480464CTDBenzo(a)pyrene results in increased expression of SLC3A2 mRNA

PMID:19770486, PMID:21569818
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.