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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3073
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc3a2
Name: solute carrier family 3 member 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SLC3A2 mRNA

PMID:22298810
increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC3A2 mRNA

PMID:16054898, PMID:18178546, PMID:20959002, PMID:21215274
affects expressionISORGD:7357176480464CTDTetrachlorodibenzodioxin affects the expression of SLC3A2 mRNA

PMID:21570461
increases expressionISORGD:7357166480464CTDTetrachlorodibenzodioxin results in increased expression of SLC3A2 mRNA

PMID:17517823, PMID:20106945, PMID:21632981, PMID:22903824, PMID:23625689, PMID:26238291, PMID:26621329
increases expressionISORGD:7357176480464CTDTetrachlorodibenzodioxin results in increased expression of SLC3A2 mRNA

PMID:18796159
multiple interactionsISORGD:7357166480464CTD2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC3A2 mRNA]

PMID:23625689
multiple interactionsISORGD:7357176480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC3A2 mRNA

PMID:17942748
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.