Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:50292
Term: cadmium sulfate
Definition: A cadmium salt that has formula CdO4S.
Chemical ID: MESH:C037123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases phosphorylationEXP 6480464CTDcadmium sulfate results in increased phosphorylation of MAPK3 proteinPMID:22767315
Mapk3multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK3 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK3 protein]PMID:11880281 PMID:22767315
Mapk3increases phosphorylationISOMapk3 (Mus musculus)6480464CTDcadmium sulfate results in increased phosphorylation of MAPK3 proteinPMID:20600713
Mapk3multiple interactionsISOMAPK3 (Homo sapiens)6480464CTDcadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MAPK3 mutant form inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; U 0126 inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]PMID:22094458 PMID:22142850
Mapk3multiple interactionsISOMapk3 (Mus musculus)6480464CTDcadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 proteinPMID:22094458
Go Back to source page   Continue to Ontology report