GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk3 | multiple interactions | EXP | | 6480464 | CTD | fulvestrant inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [notoginsenoside R1 results in increased phosphorylation of MAPK3 protein]; fulvestrant inhibits the reaction [Promegestone results in increased phosphorylation of MAPK3 protein] | PMID:15531431 PMID:16020483 PMID:22230296 PMID:24437944 PMID:27025157 | Mapk3 | increases phosphorylation | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | fulvestrant results in increased phosphorylation of MAPK3 protein | PMID:24440569 | Mapk3 | multiple interactions | ISO | MAPK3 (Homo sapiens) | 6480464 | CTD | [U 0126 results in decreased phosphorylation of [MAPK3 protein co-treated with MAPK1 protein]] which results in decreased susceptibility to Fulvestrant; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MAPK3 protein modified form]; Fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Dibutyl Phthalate] results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Atrazine results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bis(4-oxyphenyl)sulfide results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of MAPK3 protein modified form]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [luteolin-7-glucoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of MAPK3 protein]]; Fulvestrant inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [tetrachlorodian results in increased phosphorylation of MAPK3 protein] | PMID:15319301 PMID:17125913 PMID:17689939 PMID:19041697 PMID:20875696 PMID:20962025 PMID:24440569 PMID:25128825 PMID:25616260 PMID:26006730 PMID:26133781 PMID:27071941 PMID:27880919 PMID:28736254 PMID:29383186 PMID:30590302 PMID:30682495 PMID:31059536 PMID:31381935 PMID:33582643 PMID:36089060 | Mapk3 | multiple interactions | ISO | Mapk3 (Mus musculus) | 6480464 | CTD | Fulvestrant affects the reaction [sodium arsenite affects the expression of MAPK3 mRNA]; Fulvestrant affects the reaction [sodium arsenite affects the expression of MAPK3 protein]; Fulvestrant inhibits the reaction [4-nonylphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [octylphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant promotes the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein] | PMID:18417718 PMID:21278053 PMID:24495410 PMID:25461906 PMID:28446726 PMID:28849599 PMID:30684567 | | ||||||||||||||||||||||
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