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GENE - TERM ANNOTATION REPORT

RGD ID: 3033
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad4
Name: SMAD family member 4
Acc ID: GO:0001228
Term: DNA-binding transcription activator activity, RNA polymerase II-specific
Definition: A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
Definition Source(s): GOC:aruk, GOC:txnOH-2018, PMID:20737563, PMID:27145859
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad4enablesISOSMAD4 (Homo sapiens)1624291RGD PMID:18832382 PMID:9389648

PMID:18832382 PMID:9389648
Smad4enablesISOSmad4 (Mus musculus)1624291RGDUniProtKB:P43694 MGI:3851310 PMID:19366691 MGI:4946551 PMID:21330551

MGI:3851310 MGI:4946551 PMID:19366691 PMID:21330551
Smad4enablesIEAUniProtKB:P97471 or ensembl:ENSMUSP000000253931600115EnsemblGO_REF:0000107

GO_REF:0000107
Smad4enablesIEAUniProtKB:Q13485 or ensembl:ENSP000003415511600115EnsemblGO_REF:0000107

GO_REF:0000107
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