GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Smad3 | increases phosphorylation | ISO | SMAD3 (Homo sapiens) | 6480464 | CTD | Glucose results in increased phosphorylation of SMAD3 protein | PMID:26045780 | Smad3 | multiple interactions | ISO | SMAD3 (Homo sapiens) | 6480464 | CTD | 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Glucose results in increased phosphorylation of SMAD3 protein]; Glucose results in increased phosphorylation of and affects the localization of SMAD3 protein; protocatechualdehyde inhibits the reaction [Glucose results in increased phosphorylation of and affects the localization of SMAD3 protein] | PMID:17597607 PMID:26045780 | |
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