GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lox | increases expression | EXP | | 6480464 | CTD | cobaltous chloride results in increased expression of LOX mRNA | PMID:23161664 | Lox | multiple interactions | EXP | | 6480464 | CTD | Cadmium Chloride inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]]; cobaltous chloride promotes the reaction [[HIF1A protein co-treated with ARNT protein] results in increased expression of LOX mRNA]; cobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]; cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of LOX mRNA]; HIF1A mutant form inhibits the reaction [cobaltous chloride results in increased expression of LOX mRNA] | PMID:23161664 | Lox | increases expression | ISO | LOX (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased expression of LOX mRNA; cobaltous chloride results in increased expression of LOX protein | PMID:24614111 | | ||||||||||||||||||||||
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