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GENE - TERM ANNOTATION REPORT

RGD ID: 3007
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Acc ID: GO:0007189
Term: adenylate cyclase-activating G protein-coupled receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lhcgrinvolved_inISOLhcgr (Mus musculus)1624291RGD MGI:5318037 PMID:10493819

MGI:5318037 PMID:10493819
Lhcgrinvolved_inIEAUniProtKB:P30730 or ensembl:ENSMUSP000000249161600115EnsemblGO_REF:0000107

GO_REF:0000107
Lhcgrinvolved_inIBAFB:FBgn0016650 or FB:FBgn0039354 or MGI:2153463 or MGI:96783 or MGI:98849 or PANTHER:PTN000689980 or Rxfp1 (Rattus norvegicus) or Fshr (Rattus norvegicus) or UniProtKB:P16473 or UniProtKB:Q906741600115GO_CentralGO_REF:0000033

GO_REF:0000033
Lhcgrinvolved_inIEAPANTHER:PTHR24372:SF11600115TreeGrafterGO_REF:0000118

GO_REF:0000118
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