GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ldlr | decreases expression | EXP | | 6480464 | CTD | Amiodarone results in decreased expression of LDLR mRNA; Amiodarone results in decreased expression of LDLR protein | PMID:12538616 PMID:8137927 PMID:9071962 PMID:9751232 | Ldlr | multiple interactions | EXP | | 6480464 | CTD | Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein] | PMID:9071962 | Ldlr | decreases expression | ISO | LDLR (Homo sapiens) | 6480464 | CTD | Amiodarone results in decreased expression of LDLR mRNA | PMID:9712728 | Ldlr | multiple interactions | ISO | LDLR (Homo sapiens) | 6480464 | CTD | Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] | PMID:9712728 | |
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