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GENE - TERM ANNOTATION REPORT

RGD ID: 2993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcat
Name: lecithin cholesterol acyltransferase
Acc ID: GO:0008203
Term: cholesterol metabolic process
Definition: The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcat IDA 1581789RGD  
Lcatacts_upstream_of_or_withinISOLcat (Mus musculus)1624291RGD PMID:9300780

PMID:9300780
Lcatacts_upstream_of_or_withinISOLCAT (Homo sapiens)1624291RGD PMID:10559507

PMID:10559507
Lcatinvolved_inISOLCAT (Homo sapiens)1624291RGD PMID:26195816 PMID:3458198 PMID:4335615

PMID:26195816 PMID:3458198 PMID:4335615
Lcatinvolved_inIEAUniProtKB:P04180 or ensembl:ENSP000002640051600115EnsemblGO_REF:0000107

GO_REF:0000107
Lcatinvolved_inIEAUniProtKB:P16301 or ensembl:ENSMUSP000000382321600115EnsemblGO_REF:0000107

GO_REF:0000107
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