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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2989
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lamp1
Name: lysosomal-associated membrane protein 1
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lamp1multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LAMP1 protein; brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LAMP1 protein]; NFE2L2 protein inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of LAMP1 protein]PMID:34695510
Lamp1multiple interactionsISOLAMP1 (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LAMP1 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LAMP1 mRNA]; NUPR1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LAMP1 mRNA]PMID:31319114
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