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GENE - TERM ANNOTATION REPORT

RGD ID: 2981
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kras
Name: KRAS proto-oncogene, GTPase
Acc ID: DOID:9000965
Term: Neoplasm Metastasis
Definition: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
Definition Source(s): MESH:D009362
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kras ISOKras (Mus musculus)11570402RGDassociated with Fibrosarcoma;mRNA,protein:decreased expression:: 
Krasdisease_progressionISOKRAS (Homo sapiens)14398745RGDassociated with colorectal cancer;DNA:mutation: : 
KrastreatmentISOKRAS (Homo sapiens)11086960RGDassociated with colorectal cancer;DNA:mutations: : 
KrastreatmentISOKRAS (Homo sapiens)14398751RGDassociated with colorectal cancer; DNA:mutation:cds: 
KrastreatmentISOKRAS (Homo sapiens)152995400RGDassociated with stomach cancer; human cells in mouse model  
Kras ISOKRAS (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:8635384
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