GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Jun | increases expression | EXP | | 6480464 | CTD | Rotenone results in increased expression of JUN mRNA | PMID:28374803 | Jun | increases phosphorylation | EXP | | 6480464 | CTD | Rotenone results in increased phosphorylation of JUN protein | PMID:27535828 PMID:30472438 | Jun | multiple interactions | EXP | | 6480464 | CTD | 1-(1-acetyl-piperidine-4-yl)-3-adamantan-1-yl-urea inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein]; Curcumin analog inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein] | PMID:27535828 PMID:30472438 | Jun | increases expression | ISO | JUN (Homo sapiens) | 6480464 | CTD | Rotenone results in increased expression of JUN protein; Rotenone results in increased expression of JUN protein modified form | PMID:32368861 | Jun | increases phosphorylation | ISO | JUN (Homo sapiens) | 6480464 | CTD | Rotenone results in increased phosphorylation of JUN protein | PMID:17324951 PMID:18242171 PMID:20594614 | Jun | multiple interactions | ISO | JUN (Homo sapiens) | 6480464 | CTD | kaempferol inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein]; PSME4 protein promotes the reaction [Rotenone results in increased expression of JUN protein]; ropinirole inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein]; Rotenone results in increased phosphorylation of and results in increased activity of JUN protein | PMID:14976342 PMID:18242171 PMID:20594614 PMID:32368861 | |
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