Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 protein]; MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 mRNA]
1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; 1,3-dimethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to IL6 promoter]; Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to IL6 promoter]; Asbestos, Crocidolite promotes the reaction [RELA protein binds to IL6 promoter]; Asbestos, Crocidolite promotes the reaction [TNF protein results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 mRNA]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; prolinedithiocarbamate inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to IL6 promoter]]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to IL6 promoter]]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [RELA protein binds to IL6 promoter]]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; TNF protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]