GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il6 | multiple interactions | EXP | | 6480464 | CTD | Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL6 protein] | PMID:18590720 | Il6 | multiple interactions | ISO | Il6 (Mus musculus) | 6480464 | CTD | Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of IL6 mRNA]; Emodin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 protein]; Emodin inhibits the reaction [Tobacco Smoke Pollution results in increased secretion of IL6 protein] | PMID:26139382 PMID:30517764 PMID:37023836 | Il6 | multiple interactions | ISO | IL6 (Homo sapiens) | 6480464 | CTD | Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of AKT1 protein]; Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of JAK1 protein]; Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of JAK2 protein]; Emodin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein] | PMID:23848338 | | ||||||||||||||||||||||
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