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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2901
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:28094
Term: 2,2,2-trichloroethanol
Definition: A chloroethanol that has formula C2H3Cl3O.
Chemical ID: MESH:C005849
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6increases expressionISOIL6 (Homo sapiens)6480464CTD2,2,2-trichloroethanol results in increased expression of IL6 proteinPMID:23041168
Il6multiple interactionsISOIL6 (Homo sapiens)6480464CTD3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [2,2,2-trichloroethanol results in increased expression of IL6 protein]PMID:23041168
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