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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2901
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:28073
Term: chromium atom
Definition: A chromium group element atom that has atomic number 24.
Chemical ID: MESH:D002857
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6decreases expressionISOIl6 (Mus musculus)6480464CTDChromium results in decreased expression of IL6 proteinPMID:16933788
Il6increases secretionISOIL6 (Homo sapiens)6480464CTDChromium results in increased secretion of IL6 proteinPMID:10619928
Il6multiple interactionsISOIl6 (Mus musculus)6480464CTD[Chromium co-treated with Linoleic Acids, Conjugated] results in decreased expression of IL6 protein; Chromium inhibits the reaction [Dietary Fats results in increased expression of IL6 protein]PMID:16933788 PMID:21134603
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