GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il6 | affects response to substance | ISO | Il6 (Mus musculus) | 6480464 | CTD | IL6 protein affects the susceptibility to Gold Sodium Thiomalate | PMID:19077085 | Il6 | decreases expression | ISO | IL6 (Homo sapiens) | 6480464 | CTD | Gold Sodium Thiomalate results in decreased expression of IL6 mRNA; Gold Sodium Thiomalate results in decreased expression of IL6 protein | PMID:19192274 | Il6 | multiple interactions | ISO | Il6 (Mus musculus) | 6480464 | CTD | IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] | PMID:19077085 | Il6 | multiple interactions | ISO | IL6 (Homo sapiens) | 6480464 | CTD | [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL6 protein | PMID:11824965 | |
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