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GENE - TERM ANNOTATION REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: DOID:9007383
Term: Chemical and Drug Induced Liver Injury
Definition: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Definition Source(s): MESH:D056486
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 ISORGD:73630611554173CTDCTD Direct Evidence: marker/mechanism, therapeutic

PMID:21094227, PMID:21735453, PMID:22107450
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.