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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:49807
Term: lead(2+)
Definition: A lead cation that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:107966480464CTD[lead chloride results in increased abundance of Lead] which results in increased expression of IL4 protein, decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IL4 protein], Lead results in increased expression of and results in increased secretion of IL4 protein

PMID:28973681, PMID:30836164
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.