GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il4 | increases expression | EXP | | 6480464 | CTD | Calcimycin results in increased expression of IL4 mRNA | PMID:17950587 | Il4 | multiple interactions | EXP | | 6480464 | CTD | Luteolin inhibits the reaction [Calcimycin results in increased expression of IL4 mRNA]; thunberginol B inhibits the reaction [Calcimycin results in increased expression of IL4 mRNA] | PMID:17950587 | Il4 | affects response to substance | ISO | IL4 (Homo sapiens) | 6480464 | CTD | IL4 protein affects the susceptibility to Calcimycin | PMID:11861792 | Il4 | increases expression | ISO | IL4 (Homo sapiens) | 6480464 | CTD | Calcimycin results in increased expression of IL4 mRNA | PMID:12789233 | Il4 | multiple interactions | ISO | IL4 (Homo sapiens) | 6480464 | CTD | [Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL4 protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; fisetin inhibits the reaction [[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL4 protein]; fisetin inhibits the reaction [Calcimycin results in increased expression of IL4 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; IL4 protein inhibits the reaction [Calcimycin results in increased metabolism of Leukotriene B4]; IL4 protein promotes the reaction [Calcimycin results in increased metabolism of Hydroxyeicosatetraenoic Acids metabolite]; kaempferol inhibits the reaction [Calcimycin results in increased expression of IL4 mRNA]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4]; Quercetin inhibits the reaction [Calcimycin results in increased expression of IL4 mRNA]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein] | PMID:11861792 PMID:12789233 PMID:1371491 PMID:16601352 PMID:18325701 PMID:21515303 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |