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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2893
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1rap
Name: interleukin 1 receptor accessory protein
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1rapdecreases expressionISOIl1rap (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of IL1RAP mRNAPMID:15894712 PMID:19770486
Il1rapdecreases methylationISOIL1RAP (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of IL1RAP 5' UTRPMID:27901495
Il1rapmultiple interactionsISOIl1rap (Mus musculus)6480464CTD[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of IL1RAP mRNAPMID:15894712
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