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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:81506
Term: 2,3,7,8-Tetrachlorodibenzofuran
Definition: A dibenzofuran that has formula C12H4Cl4O.
Chemical ID: MESH:C014211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bdecreases expressionISOIl1b (Mus musculus)6480464CTD2,3,7,8-tetrachlorodibenzofuran results in decreased expression of IL1B mRNAPMID:24713691
Il1bincreases expressionISOIl1b (Mus musculus)6480464CTD2,3,7,8-tetrachlorodibenzofuran results in increased expression of IL1B mRNAPMID:25768209
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDAHR protein promotes the reaction [2,3,7,8-tetrachlorodibenzofuran results in increased expression of IL1B mRNA]PMID:25768209
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