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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:79997
Term: GW 4064
Definition: A stilbenoid that has formula C28H22Cl3NO4.
Chemical ID: MESH:C412815
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bdecreases expressionISOIl1b (Mus musculus)6480464CTDGW 4064 results in decreased expression of IL1B mRNAPMID:23371517
Il1bincreases expressionISOIL1B (Homo sapiens)6480464CTDGW 4064 results in increased expression of IL1B mRNAPMID:31437187
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDGW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased expression of IL1B mRNA]PMID:36328986
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTDGW 4064 inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]PMID:21242261
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