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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:61070
Term: 8-chloro-2'-deoxyguanosine
Definition: An organochlorine compound comprising 2'-deoxyguanosine having a chloro substituent at position 8 of the guanine ring system.
Chemical ID: MESH:C506093
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bincreases expressionISOIl1b (Mus musculus)6480464CTD8-chloro-2'-deoxyguanosine results in increased expression of IL1B mRNAPMID:31066272
Il1bincreases secretionISOIl1b (Mus musculus)6480464CTD8-chloro-2'-deoxyguanosine results in increased secretion of IL1B proteinPMID:31066272
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