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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:6030
Term: isoniazide
Definition: A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine.
Chemical ID: MESH:D007538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bincreases expressionEXP 6480464CTDIsoniazid results in increased expression of IL1B mRNAPMID:33121995
Il1bmultiple interactionsEXP 6480464CTDchrysin inhibits the reaction [Isoniazid results in increased expression of IL1B mRNA]PMID:33121995
Il1bincreases expressionISOIL1B (Homo sapiens)6480464CTDIsoniazid results in increased expression of IL1B mRNAPMID:32816093
Il1bincreases secretionISOIL1B (Homo sapiens)6480464CTDIsoniazid results in increased secretion of IL1B proteinPMID:28444390
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