GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | EXP | | 6480464 | CTD | Fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]]; Fulvestrant inhibits the reaction [Tamoxifen inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]] | PMID:25305410 PMID:25738436 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | fulvestrant results in increased expression of IL1B mRNA | PMID:16298037 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | Fulvestrant inhibits the reaction [bisphenol A results in increased expression of IL1B mRNA]; Fulvestrant inhibits the reaction [bisphenol F results in increased secretion of IL1B protein]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of IL1B mRNA]]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of IL1B mRNA]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CCL20 protein]]; Fulvestrant inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased phosphorylation of and affects the localization of RELA protein]] | PMID:21501669 PMID:23943137 PMID:24722370 PMID:28500084 PMID:34147605 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with Fulvestrant] results in increased methylation of IL1B gene; Fulvestrant inhibits the reaction [bisphenol A affects the expression of IL1B mRNA]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [IL1B protein results in increased expression of MMP1 protein]] | PMID:20600708 PMID:31601247 PMID:35439536 | | ||||||||||||||||||||||
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