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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10multiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Isoproterenol results in decreased expression of IL10 protein]PMID:27527349
Il10affects expressionISOIL10 (Homo sapiens)6480464CTDQuercetin affects the expression of IL10 mRNAPMID:17717114
Il10increases expressionISOIl10 (Mus musculus)6480464CTDQuercetin results in increased expression of IL10; Quercetin results in increased expression of IL10 mRNAPMID:22064046 PMID:24465016
Il10multiple interactionsISOIl10 (Mus musculus)6480464CTDdorsomorphin inhibits the reaction [Quercetin promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]]; dorsomorphin inhibits the reaction [Quercetin results in increased expression of IL10 mRNA]; Quercetin promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]PMID:24465016
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTDQuercetin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]PMID:30016632
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