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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2875
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igfbp4
Name: insulin-like growth factor binding protein 4
Acc ID: CHEBI:21891
Term: N(6)-methyladenosine
Definition: A methyladenosine compound with one methyl group attached to N(6) of the adenine nucleobase.
Chemical ID: MESH:C010223
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igfbp4multiple interactionsISOIGFBP4 (Homo sapiens)6480464CTD[[METTL3 protein affects the abundance of N-methyladenosine] which affects the methylation of IGFBP4 mRNA] which affects the expression of IGFBP4 protein; [METTL3 protein affects the abundance of N-methyladenosine] which affects the expression of IGFBP4 protein; [METTL3 protein affects the abundance of N-methyladenosine] which affects the methylation of IGFBP4 mRNAPMID:35971034
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