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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2874
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
Acc ID: CHEBI:5692
Term: hexachlorobenzene
Definition: A member of the class of chlorobenzenes that is benzene in which all of the hydrogens are replaced by chlorines. An agricultural fungicide introduced in the mid-1940s and formerly used as a seed treatment, its use has been banned since 1984 under the Stockholm Convention on Persistent Organic Pollutants.
Chemical ID: MESH:D006581
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igfbp3multiple interactionsISOIGFBP3 (Homo sapiens)6480464CTD[Hydrocarbons, Chlorinated co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] affects the expression of IGFBP3 mRNAPMID:31923581
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