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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2874
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igfbp3
Name: insulin-like growth factor binding protein 3
Acc ID: CHEBI:34202
Term: 2,2',4,4',5,5'-hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C014024
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igfbp3affects expressionISOIGFBP3 (Homo sapiens)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of IGFBP3 mRNAPMID:20638727
Igfbp3decreases expressionISOIGFBP3 (Homo sapiens)6480464CTD2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of IGFBP3 mRNAPMID:22262711
Igfbp3multiple interactionsISOIGFBP3 (Homo sapiens)6480464CTD[Hydrocarbons, Chlorinated co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] affects the expression of IGFBP3 mRNAPMID:31923581
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