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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2869
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Igf1r
Name: insulin-like growth factor 1 receptor
Acc ID: CHEBI:64243
Term: monosodium L-glutamate
Definition: An optically active form of monosodium glutamate having L-configuration.
Chemical ID: MESH:D012970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igf1rincreases expressionEXP 6480464CTDSodium Glutamate results in increased expression of IGF1R mRNAPMID:7711889
Igf1rmultiple interactionsEXP 6480464CTDGH1 protein inhibits the reaction [Sodium Glutamate results in increased expression of IGF1R mRNA]PMID:7711889
Igf1rmultiple interactionsISOIgf1r (Mus musculus)6480464CTD[Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of IGF1R mRNA; Sodium Glutamate affects the reaction [Azoxymethane affects the expression of IGF1R mRNA]PMID:19001666 PMID:22223845
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