GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | multiple interactions | EXP | | 6480464 | CTD | [Hydrogen Peroxide co-treated with Ammonium Sulfate] promotes the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased expression of HMOX1] | PMID:15035594 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in increased activity of IFNG protein] which results in decreased susceptibility to Hydrogen Peroxide; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [IL13 protein co-treated with IFNG protein] results in increased abundance of Hydrogen Peroxide; Hydrogen Peroxide inhibits the reaction [IFNG protein affects the localization of STAT1 protein]; Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein] | PMID:15748169 PMID:22440610 PMID:24518246 PMID:29594315 | Ifng | multiple interactions | ISO | Ifng (Mus musculus) | 6480464 | CTD | [IL1B protein co-treated with IFNG protein] results in increased abundance of Hydrogen Peroxide; Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Hydrogen Peroxide inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; Hydrogen Peroxide promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; sulforaphane inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Hydrogen Peroxide] | PMID:12847270 PMID:19071154 | |
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