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GENE - TERM ANNOTATION REPORT

RGD ID: 2865
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ifnb1
Name: interferon beta 1
Acc ID: DOID:2377
Term: multiple sclerosis
Definition: A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Multiple_sclerosis "DO" "DO", https://ghr.nlm.nih.gov/condition/multiple-sclerosis "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifnb1treatmentISOIFNB1 (Homo sapiens)401854232RGD  
Ifnb1 ISOIFNB1 (Homo sapiens)11554173CTDCTD Direct Evidence: therapeuticPMID:10520943 PMID:12424511 PMID:12432978 PMID:23517930 PMID:27806875
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