GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ibsp | increases expression | ISO | IBSP (Homo sapiens) | 6480464 | CTD | zoledronic acid results in increased expression of IBSP protein | PMID:15324309 | Ibsp | multiple interactions | ISO | IBSP (Homo sapiens) | 6480464 | CTD | [zoledronic acid results in decreased geranoylation of RHOA protein] which results in increased expression of IBSP mRNA; geranylgeraniol inhibits the reaction [zoledronic acid results in increased expression of IBSP mRNA]; zoledronic acid inhibits the reaction [RHOA protein results in decreased expression of IBSP mRNA]; zoledronic acid results in increased expression of and results in decreased degradation of IBSP mRNA | PMID:15324309 | |
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